《英文msh詞典》v myc Oncogenes
[入口詞] v myc Oncogenes
[主題詞] Genes,myc
[英文釋義] Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon,which appears to regulate c-myc expression,is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.